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Job Req ID:  54390

Laboratory Technician

General Summary/Purpose:

A technician is sought in the Department of Neurology. This laboratory studies the pathogenesis of a subtype of Charcot-Marie-Tooth disease (CMT), which is an inherited form of peripheral neuropathy and constitutes the most common inherited neurologic disorder worldwide. The laboratory focuses on CMT type 2C, which is caused by dominant mutations in the ion channel TRPV4 and causes weakness of the arms and legs, sensory loss, and respiratory difficulties. The laboratory studies fundamental functions of TRPV4, how mutations disrupt these functions, and potential therapeutic implications for TRPV4-targeted drugs. The ultimate goal of these pursuits is to use cell culture and animal models for development of therapeutic strategies for CMT and other neurological conditions in which nerves are damaged.


Specific Duties & Responsibilities:

  • Assist in ongoing pursuits directed by the principal investigator and to independently pursue new projects related to the pathogenesis of TRPV4.
  • Performing laboratory experiments.
  • Assistance with management of transgenic mouse colonies, animal drug treatments, animal behavioral testing, animal surgical procedures, animal tissue processing and histology, maintenance of immortalized cultured cells, and generation of recombinant DNA expression vectors.
  • The ideal candidate will be highly motivated with exceptional personal initiative and communication skills.
  • Animal experiments and colony maintenance (drug treatment, behavioral testing, surgery, and histology) (60%).
  • Laboratory experiments (transient transfection, Western blotting, co-immunoprecipitation, immunohistochemistry, culture of immortalized cells) (30%)
  • Administrative duties (e.g., ordering reagents) (10%)


Minimum Qualifications (mandatory):

  • High school diploma/GED with some science coursework required.
  • Experience with molecular biology and biochemistry laboratory approaches is helpful, but not required.


Classified Title: Laboratory Technician 
Working Title: Laboratory Technician 
Role/Level/Range: ACRO40/E/02/CB 
Starting Salary Range: $15.00-$16.93 per hour; commensurate with experience
Employee group: Full Time 
Schedule: Monday-Friday/8:30am-5:00pm 
Exempt Status: Non-Exempt  
Location: 04-MD:School of Medicine Campus 
Department name: 10003524-SOM Neuro Neuromuscular 
Personnel area: School of Medicine


The successful candidate(s) for this position will be subject to a pre-employment background check.


If you are interested in applying for employment with The Johns Hopkins University and require special assistance or accommodation during any part of the pre-employment process, please contact the HR Business Services Office at jhurecruitment@jhu.edu. For TTY users, call via Maryland Relay or dial 711.


The following additional provisions may apply depending on which campus you will work.  Your recruiter will advise accordingly.


During the Influenza ("the flu") season, as a condition of employment, The Johns Hopkins Institutions require all employees who provide ongoing services to patients or work in patient care or clinical care areas to have an annual influenza vaccination or possess an approved medical or religious exception. Failure to meet this requirement may result in termination of employment.


The pre-employment physical for positions in clinical areas, laboratories, working with research subjects, or involving community contact requires documentation of immune status against Rubella (German measles), Rubeola (Measles), Mumps, Varicella (chickenpox), Hepatitis B and documentation of having received the Tdap (Tetanus, diphtheria, pertussis) vaccination. This may include documentation of having two (2) MMR vaccines; two (2) Varicella vaccines; or antibody status to these diseases from laboratory testing. Blood tests for immunities to these diseases are ordinarily included in the pre-employment physical exam except for those employees who provide results of blood tests or immunization documentation from their own health care providers. Any vaccinations required for these diseases will be given at no cost in our Occupational Health office.


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