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Job Req ID:  106117

Sr. Research Specialist

We are seeking a Sr. Research Specialist who is highly motivated, energetic and an independent individual, with an interest in developmental biology and breast cancer to work in a fast-paced and dynamic basic science lab. The Ewald Lab studies the molecular control of cancer metastasis through a combination of advanced 3D culture models and both genetically engineered (GEMM) and patient derived (PDX) models of cancer metastasis.

Specific Duties & Responsibilities

  • Design and management of both the GEMM and PDX animal colonies, which involves working independently with graduate students, postdoctoral fellows, and clinical fellows to identify strains of mice, genotypes, and patient tumor subtypes necessary for their work.
  • Maintenance of this >300 cage mouse colony involves planning and setting up breeding's, weaning mice, tagging, tailing, and genotyping mice. The cancer models require specialized data collection on tumor progression in each mouse, analysis of the results of sophisticated genetic crosses, and highly skilled small animal surgeries. These analyses require designing and updating computational databases describing the natural history of disease in the animal models and the results of molecular interventions
  • Interviewing, training, and providing hiring recommendations for undergraduate researchers, PhD rotation students, and postdoctoral candidates.
  • Teaching the basics of mouse genetics and colony management to all new lab members, teaching surgical technique, and crossing transgenic mice to generate new cancer models.
  • Monitoring and evaluating performance in the lab and communicating these assessments to Dr. Ewald.
  • Managing the capital equipment, supply and consumable purchasing, and allocation of expenditures to grants based on an understanding of which personnel relate to which project.
  • Maintaining lab compliance with and renewal of recombinant DNA, biohazard, human tissue, and ACUC animal protocols in an independent fashion.

Special Knowledge, Skills & Abilities

  • Prior experience with mice in a laboratory setting is required.
  • A willingness to work with mice daily and careful recordkeeping of their genotypes are both required.
  • Exceptional organizational ability and attention to detail are required.
  • A strong working knowledge of genetics is required.

Minimum Qualifications
  • Bachelor's Degree in Biology, Chemistry or related field.
  • Four years experience in a comparable laboratory performing relevant techniques.
  • Master's Degree, with related graduate research, may substitute for experience to the extent permitted by the JHU equivalency formula.

Preferred Qualifications
  • Experience with management of a large genetically-complex mouse colony is strongly preferred.



Classified Title: Sr. Research Specialist 
Role/Level/Range: ACRP/04/MC  
Starting Salary Range: $46,560-$64,100-$81,650 annually (commensurate with experience) 
Employee group: Full Time 
Schedule: Monday-Friday, 8:30am-5pm 
Exempt Status: Exempt 
Location: School of Medicine Campus
Department name: ​​​​​​​SOM Cell Bio Cell Biology
Personnel area: School of Medicine 


Please refer to the job description above to see which forms of equivalency are permitted for this position. If permitted, equivalencies will follow these guidelines:

JHU Equivalency Formula: 30 undergraduate degree credits (semester hours) or 18 graduate degree credits may substitute for one year of experience. Additional related experience may substitute for required education on the same basis. For jobs where equivalency is permitted, up to two years of non-related college course work may be applied towards the total minimum education/experience required for the respective job.

**Applicants who do not meet the posted requirements but are completing their final academic semester/quarter will be considered eligible for employment and may be asked to provide additional information confirming their academic completion date.

The successful candidate(s) for this position will be subject to a pre-employment background check. Johns Hopkins is committed to hiring individuals with a justice-involved background, consistent with applicable policies and current practice. A prior criminal history does not automatically preclude candidates from employment at Johns Hopkins University. In accordance with applicable law, the university will review, on an individual basis, the date of a candidate’s conviction, the nature of the conviction and how the conviction relates to an essential job-related qualification or function.


The Johns Hopkins University values diversity, equity and inclusion and advances these through our key strategic framework, the JHU Roadmap on Diversity and Inclusion.


Equal Opportunity Employer

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.


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Accommodation Information

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Johns Hopkins has mandated COVID-19 and influenza vaccines, as applicable. Exceptions to the COVID and flu vaccine requirements may be provided to individuals for religious beliefs or medical reasons. Requests for an exception must be submitted to the JHU vaccination registry. For additional information, applicants for SOM positions should visit and all other JHU applicants should visit


The following additional provisions may apply, depending on campus. Your recruiter will advise accordingly.

The pre-employment physical for positions in clinical areas, laboratories, working with research subjects, or involving community contact requires documentation of immune status against Rubella (German measles), Rubeola (Measles), Mumps, Varicella (chickenpox), Hepatitis B and documentation of having received the Tdap (Tetanus, diphtheria, pertussis) vaccination. This may include documentation of having two (2) MMR vaccines; two (2) Varicella vaccines; or antibody status to these diseases from laboratory testing. Blood tests for immunities to these diseases are ordinarily included in the pre-employment physical exam except for those employees who provide results of blood tests or immunization documentation from their own health care providers. Any vaccinations required for these diseases will be given at no cost in our Occupational Health office.


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School of Medicine - East Baltimore Campus