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Requisition ID:  117988

Sr. Research Specialist II

We are seeking a Sr. Research Specialist II to join Dr. Nagy's lab at All Children's Hospital. The primary focus in the Nagy laboratory is to study epigenomics of cell type specification and the role of macrophages in tissue regeneration, metabolism and tumor growth and metastasis. The individual in this role will apply advanced knowledge of mouse breeding and colony management, tissue culture and molecular biology (PCR, Western blot, molecular cloning), general lab organization, and training and day-to-day oversight of lab assistants.


The Sr. Research Specialist II will make intellectual contributions to the scientific research interests of the lab utilizing specialized and sophisticated instrumentation including flow cytometry and next generation sequencing based technologies (ATA-seq, ChIP-Seq, CUT and RUN, GRO-Seq etc). This individual is responsible for troubleshooting, applying specialized scientific knowledge and experience to make decisions and training/guiding other laboratory personnel. In collaboration with the PI, this individual will make project decisions that may alter research objectives and direction. This individual contributes to writing peer-reviewed manuscripts and grants and applies independent thought to make decisions with the PI. 


Specific Duties & Responsibilities

  • Develops, designs, and manages specialized research projects and/or coordinates own objectives.
  • Utilizes specialized knowledge to set up and run sophisticated instrumentation and interprets the results.
  • Performs sophisticated data analysis utilizing extensive knowledge base and varied methods experience, e.g. RNA-sequencing data, metabolomics data, proteomics data and lipidomics data
  • Conduct in vivo inflammatory studies in laboratory mice.
  • Independently develops protocol criteria.
  • Develop and follow protocols for in vitro and in vivo assays, design experiments to investigate gene function in metabolism and oversee research projects and provide oversight of trainees.
  • Help team building with other members in the lab. Will guide, direct and facilitate problem solving for entry-level lab members on day to day problems.
  • Organize a regular journal club (monthly) and invite other groups in the program to participate
  • Acts as a consultant to refine or adapt methodologies to fit research objectives.
  • Collaborates in development of new technologies, protocols and uses of equipment.
  • Advises PI on experimental design and advises on research methods.
  • Co-authors publications and grant proposals. Contributes original thoughts, hypotheses, and analysis to reports, abstracts, manuscripts, and grant proposals. 
  • Independently performs all experiments and research assays related to laboratory interests.
  • Enhance problem solving through interactions and discussions with collaborators or senior researchers at meetings and or professional presentations.
  • Collaborates with other technologists, managers and faculty both inside, and possibly outside, of JHU.
  • Makes decisions regarding research projects that require assessment, revision of objectives, or altering scientific direction; considers resources and lab priorities when making recommendations for changes to research projects.
  • Perform routine operational activities and day-to-day laboratory management, including but not limited to evaluation and acquisition of supplies and major equipment, inventory review, equipment maintenance to ensure the laboratory remains operational. Organize the weekly lab-meeting and coordinate with the PI.
  • May provide work direction to staff, including recommendations for hire/fire and evaluation of performance.


Minimum Qualifications
  • Bachelor's Degree in Biology, Biotechnology or related field.
  • Six years' experience in a comparable laboratory performing relevant techniques in the fields of molecular biology, epigenomics and genetics.
  • Additional education may substitute for required experience and additional related experience may substitute for required education beyond HS Diploma/Graduation Equivalent, to the extent permitted by the JHU equivalency formula.


Preferred Qualifications
  • Master's Degree in Molecular Biology, Biotechnology, or related field.
  • Experience with next generation sequencing based technologies (ATA_seq, RNA.Seq, ChIP-Seq) and cellular assays (flowcytometry, ELISA).
  • Experience with in vivo studies in laboratory mice.

 

 

Classified Title: Sr. Research Specialist II 
Role/Level/Range: ACRP/04/ME  
Starting Salary Range: $64,600 - $113,300 Annually (Commensurate w/exp.) 
Employee group: Full Time 
Schedule: Mon-Fri, 8.30am-5.00pm 
FLSA Status: Exempt 
Location: Florida 
Department name: ​​​​​​​All Childrens  
Personnel area: School of Medicine 

 

 

Total Rewards
The referenced base salary range represents the low and high end of Johns Hopkins University’s salary range for this position. Not all candidates will be eligible for the upper end of the salary range. Exact salary will ultimately depend on multiple factors, which may include the successful candidate's geographic location, skills, work experience, market conditions, education/training and other qualifications. Johns Hopkins offers a total rewards package that supports our employees' health, life, career and retirement. More information can be found here: https://hr.jhu.edu/benefits-worklife/.

Education and Experience Equivalency
Please refer to the job description above to see which forms of equivalency are permitted for this position. If permitted, equivalencies will follow these guidelines: JHU Equivalency Formula: 30 undergraduate degree credits (semester hours) or 18 graduate degree credits may substitute for one year of experience. Additional related experience may substitute for required education on the same basis. For jobs where equivalency is permitted, up to two years of non-related college course work may be applied towards the total minimum education/experience required for the respective job.

Applicants Completing Studies
Applicants who do not meet the posted requirements but are completing their final academic semester/quarter will be considered eligible for employment and may be asked to provide additional information confirming their academic completion date.

Background Checks
The successful candidate(s) for this position will be subject to a pre-employment background check. Johns Hopkins is committed to hiring individuals with a justice-involved background, consistent with applicable policies and current practice. A prior criminal history does not automatically preclude candidates from employment at Johns Hopkins University. In accordance with applicable law, the university will review, on an individual basis, the date of a candidate's conviction, the nature of the conviction and how the conviction relates to an essential job-related qualification or function.

Diversity and Inclusion
The Johns Hopkins University values diversity, equity and inclusion and advances these through our key strategic framework, the JHU Roadmap on Diversity and Inclusion.

Equal Opportunity Employer
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.

EEO is the Law
https://www.eeoc.gov/sites/default/files/2023-06/22-088_EEOC_KnowYourRights6.12ScreenRdr.pdf

Accommodation Information
If you are interested in applying for employment with The Johns Hopkins University and require special assistance or accommodation during any part of the pre-employment process, please contact the Talent Acquisition Office at jhurecruitment@jhu.edu. For TTY users, call via Maryland Relay or dial 711. For more information about workplace accommodations or accessibility at Johns Hopkins University, please visit https://accessibility.jhu.edu/.

Vaccine Requirements
Johns Hopkins University strongly encourages, but no longer requires, at least one dose of the COVID-19 vaccine. The COVID-19 vaccine does not apply to positions located in the State of Florida. We still require all faculty, staff, and students to receive the seasonal flu vaccine. Exceptions to the COVID and flu vaccine requirements may be provided to individuals for religious beliefs or medical reasons. Requests for an exception must be submitted to the JHU vaccination registry. This change does not apply to the School of Medicine (SOM). SOM hires must be fully vaccinated with an FDA COVID-19 vaccination and provide proof of vaccination status. For additional information, applicants for SOM positions should visit https://www.hopkinsmedicine.org/coronavirus/covid-19-vaccine/ and all other JHU applicants should visit https://covidinfo.jhu.edu/health-safety/covid-vaccination-information/.

The following additional provisions may apply, depending upon campus. Your recruiter will advise accordingly.
The pre-employment physical for positions in clinical areas, laboratories, working with research subjects, or involving community contact requires documentation of immune status against Rubella (German measles), Rubeola (Measles), Mumps, Varicella (chickenpox), Hepatitis B and documentation of having received the Tdap (Tetanus, diphtheria, pertussis) vaccination. This may include documentation of having two (2) MMR vaccines; two (2) Varicella vaccines; or antibody status to these diseases from laboratory testing. Blood tests for immunities to these diseases are ordinarily included in the pre-employment physical exam except for those employees who provide results of blood tests or immunization documentation from their own health care providers. Any vaccinations required for these diseases will be given at no cost in our Occupational Health office.
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